Play in £ at UK licensed casinos...

The Spin Room is owned and operated by Victor Chandler International, one of the UK's largest and best known betting shops.  Operating under a Gibraltar license, the casino offers Java browser-based games, so no downloads are necessary.  The interface is a little clunky, and not as nice to play as the download casinos, but for browser based games they are pretty good, and you can be playing for real money in no time.  9 games are offered, including both American and European roulette.  Give them a try. 

32 Red is a new Microgaming casino, licensed in Gibraltar and run by British Company Trafalgar Betting & Gaming Limited.  With all the bells and whistles of a typical Microgaming casino, you'll have plenty of fun playing with these guys.  Over 90 games, including all 11 Microgaming progressives, audited returns, fast download and flash games that you can play from your browser.  

Voted best UK internet casino for 2003.

William Hill is a company well known to UK punters with over 1,500 licensed betting offices in the UK and over 10,000 employees dedicated to providing customer service that is second to none.  Their online casino is pretty good too.  They use Wagerlogic/Crytologic software so their games are super, with great graphics and multiplayer capabilities.  Game range is solid with over 30 games offered, returns are audited by PriceWaterhouseCoopers, and bet limits offered are 10p to £1,500 per game making this casino ideal for high rollers.